Searchable abstracts of presentations at key conferences in endocrinology

ea0069p5 | Poster Presentations | SFENCC2020

Isolated ACTH-deficiency following immune checkpoint inhibitors: diagnostic challenges demonstrated by a clinical case

Chatzimavridou-Grigoriadou Victoria , Higham Claire E , Lorigan Paul , Dhage Shaishav S , Trainer Peter J , Adam Safwaan

Case history: A 53-year-old male with melanoma who had a previous surgical excision of his skin lesion in December 2018 was being treated with adjuvant pembrolizumab. In June 2019 his treatment changed to combination immune checkpoint inhibitor therapy (ICPi) with ipilimumab and nivolumab due to radiological recurrence.Investigations: There were no pre-ICPi endocrine investigations available. In July 2019, thyroid function tests (TFTs) showed thyroid-sti...